Sperm quality and pregnancy rate after COX-2 inhibitor therapy of infertile males with abacterial leukocytospermia

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Sperm quality and pregnancy rate after COX-2 inhibitor therapy of infertile males with abacterial leukocytospermia.

BACKGROUND Leukocytes are a frequent finding in seminal plasma of infertile males with abacterial inflammation. We evaluated the effects of treatment with rofecoxib, a cyclooxygenase-2 inhibitor, on sperm quality and pregnancy rate after intrauterine insemination (IUI) or monitored intercourse. METHODS We selected 47 infertile patients referred to our sterility centre for semen analysis. Sper...

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P-171: Pregnancy Rate after Laparoscopy in Infertile Women

Background: Infertility not only as a disease but also as a serious problem affects the family and harms its health. Approximately 50 to 80 million people in the world suffer from infertility. Laparoscopy is a golden standard which helps diagnose peritoneal and the fallopian tubal problems and treat them. Materials and Methods: In this cross-sectional study, 162 infertile women referring to the...

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Reactive oxygen species and sperm DNA damage in infertile men presenting with low level leukocytospermia

BACKGROUND Leukocytes contribute directly and indirectly to reactive oxygen species (ROS) production. Although leukocytospermia is defined as the presence of ≥ 1 × 106 white blood cells/mL (WBC/mL) in a semen sample, the presence of less than 1×10(6) WBC/mL (low-level leukocytospermia) can still produce a detectable amount of ROS, impairing sperm function and lowering the chances of pregnancy. ...

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Sperm quality improvement after natural anti-oxidant treatment of asthenoteratospermic men with leukocytospermia.

AIM To study the immune-modulating and anti-oxidant effects of beta-glucan, papaya, lactoferrin, and vitamins C and E on sperm characteristics of patients with asthenoteratozoospermia associated with leucocytosis. METHODS Fifty-one patients referred to our Sterility Center for semen analysis were selected. Sperm parameters were assessed before and after patient's treatment with beta-glucan, l...

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P-59: Effect of Microsurgical Varicocelectomy on Sperm Chromatin Packaging,Miscarriage and Pregnancy Rate in Infertile Men with Varicocele

Background: Although the pathophysiology of the testicular damage associated with varicocele remains unclear, but varicocelectomy is considered a suitable technique for the treatment of individuals with clinical varicocele. The current study was designed to assessed semen parameters, chromatin packaging, and pregnancy outcome before and after varicocelectomy. Materials and Methods: Semen sample...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2007

ISSN: 1460-2350,0268-1161

DOI: 10.1093/humrep/del490